What is the difference between femara and clomid

Lowering estrogen can help knock out breast cancer in some women—and it can also help stimulate those egg follicles in TTC women. There are some other special situations in which letrozole may be prescribed over clomid. Per Dr. Diaz, letrozole in combination with injectable fertility drugs is the preferred IVF treatment for women diagnosed with breast cancer, or for women seeking to freeze their eggs before cancer therapy begins.

A typical dose of letrozole is 2. In the battle of Femara vs. Elena Donovan Mauer is a writer and editor passionate about helping people through their fertility journey. The Femara vs. Polycystic Ovarian Syndrome PCOS is the most common cause of anovulatory infertility and also the most common diagnosis of infertility in general. Clomid has historically been used as the first-line fertility treatment for patients with PCOS or other ovulatory issues. However, recent research suggests that Letrozole may produce similar, if not better, results for inducing ovulation and producing live births for these patients.

During the study, women received Letrozole treatment, and women received Clomiphene treatment for five days starting on day three of their cycle for up to 5 cycles. The women in the Letrozole group had a cumulative ovulation rate of The women in the clomiphene group ovulated Other studies, have showed similar results. A study published in on anovulatory women with PCOS also compared the effectiveness of Letrozole and Clomid on inducing ovulation. Researchers found that both drugs produced similar ovulation rates, However, they still concluded that Letrozole is a better alternative for ovulation induction in anovulatory women with PCOS because it produced higher pregnancy rates, shorter time to pregnancy, and lower chances of multiple pregnancies due to higher instances of mono-follicular growth.

Patients may be Clomid resistant for several different reasons. Patients with a body mass index BMI of over 25 have a decreased chance of Clomid working. Patients with hyperprolactinemia high levels of prolactin in the blood also may not respond well to Clomid. Women with PCOS are the most common to experience Clomid resistance, especially those who are diagnosed with insulin resistance or with hyperandrogenic levels. Of the women treated with Letrozole, Of the women treated with Clomiphene, only 72 In another study, researchers compared the effects of Letrozole and Clomiphene as first-line ovulation induction drugs to treat infertile PCOS women.

The patients treated with Letrozole experienced a pregnancy rate nearly three times that of the Clomiphene group. The pregnancy rates were Both Clomid and Letrozole can help women with unexplained infertility to achieve pregnancy.

Conflicting studies exist supporting the efficacy of both Clomid and Letrozole to improve pregnancy and live birth rates in women with unexplained infertility. In most studies, Clomiphene and Letrozole treatment produce statistically similar results.

One of the studies they reviewed was published in the NEJM in The study compared the effects of Clomiphene and Letrozole on patients with unexplained infertility who underwent timed intrauterine inseminations for up to 4 monthly menstrual cycles or until they became pregnant or discontinued treatment.

There was a statistically significant difference between pregnancy rates, but the live birth rates were similar. The live birth rates were slightly lower in the women who took Letrozole, but the results were considered statistically similar by researchers.

Researchers concluded that Clomiphene is at least as successful as Letrozole for treating patients with unexplained infertility. In another study, researchers also compared the efficacy of Clomiphene and Letrozole to treatment on women with unexplained infertility.

The results of the randomized control trial indicated that Letrozole may improve implantation and pregnancy rates in women with unexplained infertility. More than double the percentage of women treated with Letrozole achieved pregnancy In addition to the higher pregnancy rate, the group treated with Letrozole also saw a statistically significant improvement in endometrial receptivity. See in Google Maps.

Skip to content According to Randy S. Intrauterine Insemination IUI IUI — Intrauterine Insemination — is commonly prescribed as a first treatment option for women under 35 who have been unable to conceive after one year of regular, unprotected sexual intercourse. Previous Previous. Next Continue. Similar Posts It is normal to experience mild to moderate abdominal bloating from time to time; eating too much or eating an unusual food can cause bloating with no underlying problem being present.

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